Breast Cancer

MANAGEMENT OF AXILLA

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Anatomy of the lymph drainage of the breast
Rationale behind the need for the treatment of the axilla in breast cancer
Axillary clearance versus axillary node sampling
Sentinel node biopsy
In-house policy on management of the axilla in breast cancer
Complications of axillary surgery
Surgical management of axilla in patients with breast cancers

 

Axillary clearance versus axillary node sampling

The protagonists of axillary sampling argue that axillary clearance represents an over treatment in a significant proportion ( 60% ) of patients who will be found to be free of nodal disease on histological examination. The sampling of the axilla allows to define the group with nodal disease who would benefit from further treatment to the axilla mainly in the form of a formal clearance or radiotherapy. They argue that there is little evidence to suggest that axillary control imparts better overall survival in these patients.

Against the policy of axillary sampling is the reportedly high rate of failure to retrieve nodes by the dissection ( 18-30% ). Furthermore, skip metastasis occurs in no more than 5% of the cases (that is, involvement of higher levels in absence of disease at level l) but the presence of metastasis in the nodes at level l means that there is a 45% risk of involvement of the higher groups which will then need to be treated. Treatment would then involve a formal clearance or radiotherapy. The latter raises the risk of lymphoedema from 2-6% with surgery alone to 40% with the addition of radiotherapy.

Axillary clearance offers the most effective chance of achieving local control of the disease and although this has not shown to confer a survival advantage, it does mean a lot to the patient in terms of psychological well-being. It is therefore our policy to advocate axillary clearance in patients under the age of 65 with invasive cancer. In the older patient good disease control can be obtained with hormonal manipulation with anti-oestrogens and therefore axillary clearance is not undertaken routinely.

If you require further advice or information please contact the
Macmillan Breast Care Nurses, Hazel Ricard and Hilary Rickwood on 020 8565 5885

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